Elihu H Estey Selected Research

Exanthema (Rash)

4/2014	Preclinical and early clinical evaluation of the oral AKT inhibitor, MK-2206, for the treatment of acute myelogenous leukemia.
1/2008	Phase I study of alternate-week administration of tipifarnib in patients with myelodysplastic syndrome.
4/2004	Phase II study of R115777, a farnesyl transferase inhibitor, in myelodysplastic syndrome.
3/2003	Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias.

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Elihu H Estey Research Topics

Disease

86	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2022 - 02/2002
24	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022 - 06/2002
23	Neoplasms (Cancer) 06/2022 - 10/2003
10	Leukemia 07/2015 - 02/2002
9	Acute Promyelocytic Leukemia 11/2019 - 03/2002
5	Infections 01/2022 - 11/2009
5	Residual Neoplasm 02/2016 - 03/2011
4	Exanthema (Rash) 04/2014 - 03/2003
3	Hemorrhage 11/2019 - 02/2009
3	Hematologic Neoplasms (Hematological Malignancy) 02/2008 - 05/2004
3	Myeloid Leukemia (Leukemia, Myelocytic) 09/2003 - 03/2003
2	Mycoses (Diseases, Fungus) 01/2022 - 01/2006
2	Fever (Fevers) 01/2020 - 01/2008
2	Mucositis 01/2020 - 03/2003
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020 - 07/2015
2	Cytopenia 01/2019 - 07/2014
2	Neutropenia 07/2016 - 04/2014
2	Pathologic Complete Response 11/2012 - 06/2002
2	Diarrhea 01/2008 - 03/2003
2	Fatigue 01/2008 - 04/2004
2	Hyperbilirubinemia 10/2005 - 03/2003
1	Bacteremia 01/2022
1	Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive) 10/2020
1	Disease Progression 01/2020
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 01/2020
1	Philadelphia Chromosome 01/2020
1	Thrombocytopenia (Thrombopenia) 12/2017
1	Hypoalbuminemia 12/2017
1	Hypersensitivity (Allergy) 07/2016
1	Hypoxia (Hypoxemia) 07/2015
1	Central Nervous System Diseases (CNS Diseases) 03/2015
1	Graft vs Host Disease (Graft-Versus-Host Disease) 04/2014
1	Cross Infection (Nosocomial Infection) 01/2013

Drug/Important Bio-Agent (IBA)

20	Cytarabine (Cytosar-U)FDA LinkGeneric 06/2022 - 06/2002
12	Gemtuzumab (Mylotarg)FDA Link 06/2022 - 06/2002
10	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 06/2022 - 12/2008
7	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 06/2015 - 06/2002
6	Mitoxantrone (Novantrone)FDA LinkGeneric 06/2022 - 11/2012
5	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/2019 - 06/2002
4	Cladribine FDA LinkGeneric 06/2022 - 11/2018
4	Clofarabine (Clolar)FDA Link 01/2020 - 01/2013
4	fludarabineIBA 01/2020 - 12/2008
4	Pharmaceutical PreparationsIBA 01/2018 - 12/2005
4	Biological ProductsIBA 03/2013 - 08/2002
3	Arsenic Trioxide (Trisenox)FDA Link 11/2019 - 04/2007
3	Azacitidine (5 Azacytidine)FDA Link 01/2014 - 10/2007
2	Phosphotransferases (Kinase)IBA 01/2020 - 06/2009
2	BilirubinIBA 12/2019 - 01/2008
2	AnthracyclinesIBA 11/2018 - 04/2006
2	Pravastatin (Pravachol)FDA LinkGeneric 06/2015 - 11/2013
2	AntibodiesIBA 07/2014 - 01/2013
2	Vorinostat FDA Link 01/2014 - 05/2012
2	Core Binding Factors (Core-Binding Factor)IBA 05/2012 - 12/2008
2	tipifarnib (R115777)IBA 01/2008 - 04/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2004 - 11/2002
2	promyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinIBA 03/2004 - 03/2004
2	EnzymesIBA 10/2003 - 11/2002
2	ImmunosorbentsIBA 10/2003 - 11/2002
2	troxacitabineIBA 05/2003 - 03/2003
1	Hemoglobins (Hemoglobin)IBA 01/2022
1	NucleotidesIBA 01/2022
1	posaconazole FDA Link 01/2022
1	Fluconazole (Zonal)FDA LinkGeneric 01/2022
1	Lamin Type B (Lamin B)IBA 01/2022
1	Chimeric Antigen ReceptorsIBA 01/2020
1	Decitabine FDA Link 01/2020
1	pembrolizumabIBA 01/2020
1	CPX-351IBA 01/2018
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2017
1	Member 1 Group A Nuclear Receptor Subfamily 6IBA 07/2017
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 07/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2015
1	pimonidazoleIBA 07/2015
1	ProdrugsIBA 07/2015
1	Carbonic Anhydrase IXIBA 07/2015
1	Bendamustine Hydrochloride FDA Link 08/2014
1	MK 2206IBA 04/2014
1	Methotrexate (Mexate)FDA LinkGeneric 04/2014
1	Tacrolimus (Prograf)FDA LinkGeneric 04/2014
1	treosulfanIBA 04/2014
1	Etoposide (VP 16)FDA LinkGeneric 11/2013
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2013
1	MicroRNAs (MicroRNA)IBA 04/2013
1	Immunoconjugates (Immunoconjugate)IBA 01/2013
1	alvocidib (flavopiridol)IBA 11/2012
1	N-(2-naphthalene)sulfonyl-DL-tryptophan (A 91)IBA 11/2012

Therapy/Procedure

42	Therapeutics 01/2022 - 02/2002
26	Drug Therapy (Chemotherapy) 06/2022 - 01/2003
14	Cell Transplantation 11/2020 - 03/2011
9	Induction Chemotherapy 07/2022 - 01/2006
4	Hematopoietic Stem Cell Transplantation 10/2020 - 03/2002
4	Salvage Therapy 11/2019 - 02/2009
2	Ambulatory Care (Outpatient Care) 01/2021 - 01/2019
2	Transplantation 02/2016 - 10/2003
2	Remission Induction 06/2011 - 09/2003
2	Palliative Care (Palliative Therapy) 03/2008 - 03/2002
1	Catheters 01/2022
1	Precision Medicine 01/2018
1	Cranial Irradiation 03/2015
1	Homologous Transplantation 11/2012